Day 10 Introduction, Drug discovery pipeline: Target identification

Recorded Sessions

Day 1: Ice-breaking Session on Bioinformatics Global Tools and Techniques (62:17)
Day 2 : Scope & Opportunities in Bioinformatics: India & Abroad (61:53)
Day 3 : Understanding Key Terminology in Bioinformatics Databases (60:08)
Day 4 Carbohydrates and Proteins Demo on tools: Cheminformatics (65:46)
Day 5 Lipids and Nucleic acids Demo on tools: ChemDraw & ChemSketch (63:44)
Day 6 Primary Sequences – DNA, RNA, and Proteins Demo on tools: NCBI, EMBL, DDBJ, and SBI (65:05)
Day 7 Secondary Structures – DNA, RNA, and Proteins Demo on tools: GORV, Swiss model, I-TASSER, Phyre2 (60:41)
Day 8 Tertiary Structures – Stability, folding, and misfolding Demo on tools: Protein Data Bank (PDB), EMBL and SBI (56:18)
Day 9 Biochemical and Metabolic pathway analysis Demo on tools: KEGG, WikiPathways and Reactome database (64:58)
Day 10 Introduction, Drug discovery pipeline: Target identification and validation, Lead identification and optimization, Virtual screening Demo: IMPPAT and Dr. Duke's Phytochemical and Ethnobotanical databases for Phytochemistry Research. (67:05)
Day 11 ADMET Studies for lead optimization. Demo on tools: SWISS-ADME, Analysis, and Interpretation; Boiled-Egg Model (71:33)
Day 12 Introduction to protein and modelling concepts, types, homology modelling, and the ab-initio method. Demo on tools: PDB tools, Swiss ExPaSy (59:59)
Day 13 Constructing a Phylogenetic Tree- Demo on tools: ClustalW, Clustal Omega (63:15)
Day 14 QSAR Studies and Interpretation of Docking Demo on Molecular docking software: Patchdock, Autodock, ClusPro web server (63:34)
DAY 15 Introduction to Molecular Dynamics and Simulation (MDS). (59:30)
DAY 16 Pre-clinical (Bacterial, Fly, Plants, and Murine models), Human Clinical Trials for drug discovery, Functional genomics, and Comparative genomics. Demo on the tool: Differential expression analysis on bacterial genome. (66:45)
DAY 17 Protein-protein interaction network, STRING, Network terminology, Pathway enrichment analysis Demo on the tool: STRING and Cytoscape. (71:11)
DAY 18 Human Genome project, Bacterial Genomics, Human Microbiome, and Epigenetics Demo on database: Ensembl Bacteria, MicrobiomeDB (63:09)
DAY 19 Sanger sequencing, Next Generation Sequencing: DNA Sequencing, RNA Sequencing. miRNA Analysis. Demo on the tool: Databases: dbSNP, Clinvar, Genome browsers: UCSC and Ensembl (61:33)
DAY 20 Publication types, formats, and journals Demo on the tool: Elsevier, Springer, Wiley, MDPI, and Bentham Sciences (58:35)
DAY 21 Research made easy with Artificial Intelligence (AI & ML) Demo on the tool: Applications of ChatGPT in BioResearch (59:38)
DAY 22 Selection of the journal and indexing Demo on the tool: Journal finder (35:13)
DAY 23 Submission, Revision, and re-submission process Demo on tool: Editorial Manager (62:53)
DAY 24 Structure and ingredients of proposal writing (52:35)
DAY 25 Networking and funding from (govt./ private/ industrial partners) (49:34)

Day 10 Introduction, Drug discovery pipeline: Target identification and validation, Lead identification and optimization, Virtual screening Demo: IMPPAT and Dr. Duke's Phytochemical and Ethnobotanical databases for Phytochemistry Research.